| 08/19/2021 | at Murray St. | L | 1-6 | 0-1-0, 0-0-0 | 0-0-0 | 123 | Grace O'Keefe (1) (Jacqueline Baetz)
|
| 08/22/2021 | at Kansas City | L | 1-2 | 0-2-0, 0-0-0 | 0-0-0 | 377 | Kate Schroeder (1) (Isabel Burke , Grace O'Keefe)
|
| 08/26/2021 | vs Arkansas St. | W | 1-0 | 1-2-0, 0-0-0 | 0-0-0 | 107 | Kate Schroeder (2) (Grace O'Keefe)
|
| 08/29/2021 | at Tulsa | T | 2-2 | 1-2-1, 0-0-0 | 0-0-0 | 182 | Anna Durnin (1)
Kennady Orlick (1) (Grace O'Keefe)
|
| 09/02/2021 | vs Oral Roberts | W | 2-1 | 2-2-1, 0-0-0 | 0-0-0 | 113 | Kennady Orlick (2) (Anna Durnin , Sierra Fury)
Maddie Augustine (1) (Sierra Fury)
|
| 09/05/2021 | vs Louisiana Tech | W | 1-0 | 3-2-1, 0-0-0 | 0-0-0 | 105 | Jenna Anderson (1) (Grace O'Keefe)
|
| 09/09/2021 | at Saint Louis | T | 0-0 | 3-2-2, 0-0-0 | 0-0-0 | 789 | Â |
| 09/12/2021 | vs Omaha | T | 1-1 | 3-2-3, 0-0-0 | 0-0-0 | 167 | Sierra Fury (1) (Maddie Augustine , Grace O'Keefe)
|
| 09/17/2021 | at Southern Ill. | W | 3-0 | 4-2-3, 1-0-0 | 1-0-0 | 245 | Isabel Burke (1) (Grace O'Keefe)
Kaeli Benedict (1) (Anna Durnin)
Grace O'Keefe (2)
|
| 9/19/2021 | at Southeast Missouri | L | 0-1 | 4-3-3, 1-0-0 MVC | 1-0-0 MVC | 213 | Â |
| 09/29/2021 | vs Illinois St. | L | 0-1 | 4-4-3, 1-1-0 | 1-1-0 | 87 | Â |
| 10/03/2021 | vs Valparaiso | L | 1-2 | 4-5-3, 1-2-0 | 1-2-0 | 111 | Anna Durnin (2) (Grace O'Keefe)
|
| 10/9/2021 | at Loyola Chicago | T | 0-0 | 4-5-4, 1-2-1 MVC | 1-2-1 MVC | 412 | Â |
| 10/13/2021 | vs UNI | L | 0-2 | 4-6-4, 1-3-1 | 1-3-1 | 33 | Â |
| 10/17/2021 | at Indiana St. | L | 1-3 | 4-7-4, 1-4-1 | 1-4-1 | 127 | Abby Couch (1) (Iraia Arrue)
|
| 10/23/2021 | vs Drake | W | 3-2 | 5-7-4, 2-4-1 | 2-4-1 | 350 | Grace O'Keefe (2)
Kaeli Benedict (3) (Abby Couch , Jacqueline Baetz)
Kaeli Benedict (3) (Abby Couch)
|
| 10/28/2021 | at Evansville | T | 0-0 | 5-7-5, 2-4-2 | 2-4-2 | 275 | Â |
